Situated at the north of Armenia, Lori makes a combination of mountain ranges, such as Javakheti, Bazum, Pambak, Gugark, Halab and Somkheti, and the Lori plateau. The highest point of the province is Mount Achkasar of the Javakheti range with a height of 3196 meters. The lowest point is 380 meters in the valley of Debed at the northeast of the province.
Over 60% of the province are the arable lands and pastures, while majority of the rest are covered by deciduous forest and juniper woodland.
Flat parts of the region are nevertheless cut by deep canyons, formed by large rivers, which form the main water resource of the province: Debed river with its tributaries Dzoraget, Pambak and Marts.
The climate in most part of the province is characterized with extremely cold snowy winters and mild summers. The annual precipitation level is between 600 and 700 mm (24 and 28 in).
The wildlife sanctuary of the area are aimed at protection of alpine species as Caucasian Black Grouse and Wallcreeper, as well as regional endemic - the Caucasian Rhododendron.